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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 841-852 of 7,264
Drug study icon
CompletedNCT05615948

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Official study title

An Open-Label Clinical Trial of Simultaneous Administration of Oral Aspirin and Ketamine as Adjunct to Oral Antidepressant Therapy in Treatment-Resistant Depression

This study has finished and is no longer accepting participants.

In Brooklyn
DepressionMedication studyAges 18–89
Countries
United States
Sponsor
Theresa Jacob, PhD, MPH
Drug study icon
CompletedACTRN12624000128594

Assessing the effects of Lysergic acid diethylamide (LSD) microdosing in people experiencing depression (LSDDEP2)

Official study title

A randomised, double-dummy, triple-blind, active placebo-controlled, parallel groups, trial of LSD microdosing in patients with major depressive disorder (LSDDEP2).

This study has finished and is no longer accepting participants.

In New Zealand
DepressionInterventional studyAges 21–65
Countries
New Zealand
Sponsor
The University of Auckland
Drug study icon
TerminatedACTRN12622000881730

Low-dose naltrexone as an adjunctive treatment in major depressive disorder.

Official study title

A randomised, double-blind, placebo-controlled, hybrid parallel arm study of low-dose naltrexone as an adjunctive anti-inflammatory treatment for major depressive disorder

This study ended early.

In New Zealand
DepressionInterventional studyAges 18–55
Countries
New Zealand
Sponsor
University of Auckland
Drug study icon
Not recruitingISRCTN10974027

Safety of DMT with psychological support, with or without SSRIs, for depression

About this title

Safety, tolerability, pharmacokinetics, pharmacodynamics and exploratory efficacy of intravenous dosing of SPL026 drug product (N, N-dimethyltryptamine fumarate; DMT Fumarate [A Serotonergic Psychedelic]) alone or in combination with selective serotonin reuptake inhibitors in patients with major depressive disorder

Read the official source — ISRCTN10974027

This study isn't currently recruiting.

In United Kingdom
DepressionResearch studyAges 18–99
Countries
United Kingdom
Sponsor
Cybin UK Ltd
Biological study icon
RecruitingEUCTR 2018-001622-26

A randomized, double-blind, placebo-controlled, multicenter clinical trial to assess safety and effectiveness of Liposom in enhance and speed up response to antidepressant therapy with citalopram i...

This study transferred to CTIS. HopeStage uses that newer record for the displayed status. A country's status does not guarantee that an individual site accepts participants.

Multiple locations, including Avezzano
DepressionHistorical research record
Countries
Italy
Sponsor
FIDIA FARMACEUTICI S.P.A.
Biological study icon
Not Yet RecruitingEUCTR 2020-005162-33

Targeting inflammation in depression using minocycline: a patient stratification approach using peripheral inflammatory biomarkers, PET and MRI

This study isn't recruiting yet.

This study transferred to CTIS. HopeStage uses that newer record for the displayed status. A country's status does not guarantee that an individual site accepts participants.

In Brescia
DepressionHistorical research record
Countries
Italy
Sponsor
IRCCS CENTRO SAN GIOVANNI DI DIO - FATEBENEFRATELLI AFFERENTE ALLA PROVINCIA LOMBARDO VENETA ORDINE OSPEDALIERO DI SAN G

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.