Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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Showing 1-25 of 1,371
RecruitingNCT04777357

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolarity type I.

This study is comparing Cariprazine with placebo for people with Depression or Bipolarity I. Participants receive Cariprazine or placebo and complete study visits and assessments.

BipolarityDrugFrom 10 Years to 17 Years
Countries
United States, Russian Federation
Sponsor
AbbVie
Condition
Bipolarity
RecruitingNCT07105111

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

This study is looking at care and outcomes for people with depression, psychosis, or bipolarity. Taking part may give some people access to Valbenazine, but direct benefit is not guaranteed.

SchizophreniaDrugOver 18 Years
Countries
United States
Sponsor
Neurocrine Biosciences
Condition
Schizophrenia
RecruitingNCT06656416

ALTO-100 in Bipolarity With Depression (BD-D)

This study is looking at care and outcomes for people with bipolarity I or II With a Major Depressive Episode. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

BipolarityDrugFrom 18 Years to 70 Years
Countries
United States
Sponsor
Alto Neuroscience
Condition
Bipolarity
RecruitingNCT05849402

Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolarity type II

This study is looking at care and outcomes for people with Bipolarity II, Most Recent Episode Major Depressive, Current Depressive Episode, or Treatment Resistant Depression. Some participants may receive Sham aiTBS instead of the study treatment, and direct benefit is not guaranteed.

DepressionDeviceFrom 18 Years to 80 Years
Countries
United States
Sponsor
Stanford University
Condition
Depression
RecruitingNCT06706232

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolarity II Depression and Suicidality

This study is looking at whether questionnaires and follow-up can help people with Bipolarity II, Depression in bipolarity, or Suicidality. Participants receive a study treatment and complete follow-up visits and assessments.

BipolarityDrugFrom 25 Years to 70 Years
Countries
United States
Sponsor
The University of Texas Health Science Center, Houston
Condition
Bipolarity
RecruitingNCT05491538

Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

This study is looking at whether a digital support tool can help people with Schizophrenia, bipolarity, major depression, or Stress Disorder, Post-Traumatic. Participants take part in the therapy or support program and complete follow-up questionnaires or assessments.

DepressionBehavioralOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
RecruitingNCT03522545

Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Depression in bipolarity

This study is comparing Allogeneic Bone Marrow Derived Multipotent Mesenchymal Stromal Cells (MSCs) with placebo for people with Treatment-resistant Depression in bipolarity. Participants receive Allogeneic Bone Marrow Derived Multipotent Mesenchymal Stromal Cells (MSCs) or placebo and complete study visits and assessments.

DepressionBiologicalFrom 18 Years to 65 Years
Countries
United States
Sponsor
The University of Texas Health Science Center, Houston
Condition
Depression
Enrolling By InvitationNCT06823024

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

This observational study is following people with depression, anxiety, or bipolarity to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.

DepressionOtherFrom 18 Years to 68 Years
Countries
United States
Sponsor
Psyrin Inc.
Condition
Depression
RecruitingNCT03217110

Cerebellar Stimulation and Cognitive Control

This observational study is following people with depression, psychosis, or bipolarity to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.

SchizophreniaDeviceFrom 18 Years to 90 Years
Countries
United States
Sponsor
Krystal Parker, PhD
Condition
Schizophrenia
RecruitingNCT07359157

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

This study is looking at whether a digital support tool can help people with Serious Mental Illness, psychosis, Depression, or Bipolar. Participants take part in the therapy or support program and complete follow-up questionnaires or assessments.

BipolarityBehavioralOver 18 Years
Countries
United States
Sponsor
Massachusetts General Hospital
Condition
Bipolarity
RecruitingNCT02919280

Dallas 2K: A Natural History Study of Depression

This observational study is following people with Depression or Depression in bipolarity to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.

DepressionOtherOver 10 Years
Countries
United States
Sponsor
University of Texas Southwestern Medical Center
Condition
Depression
RecruitingNCT06599099

Deep Brain Stimulation of Treatment-Resistant Depression in bipolarity

This observational study is following people with Depression in bipolarity to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.

BipolarityDeviceFrom 22 Years to 64 Years
Countries
United States
Sponsor
Wayne Goodman MD
Condition
Bipolarity
RecruitingNCT05240352

Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Depression in bipolarity

This study is looking at care and outcomes for people with Anhedonia. Some participants may receive sham tDCS instead of the study treatment, and direct benefit is not guaranteed.

BipolarityDeviceFrom 18 Years to 50 Years
Countries
United States
Sponsor
The University of Texas Health Science Center, Houston
Condition
Bipolarity
WithdrawnNCT05060549

Dopamine D3 Receptor Occupancy in Depression in bipolarity

This study is looking at whether a digital support tool can help people with Depression in bipolarity. Participants receive a study treatment and complete follow-up visits and assessments.

BipolarityOtherFrom 18 Years to 60 Years
Countries
United States
Sponsor
New York State Psychiatric Institute
Condition
Bipolarity
Active Not RecruitingNCT05877716

EPI-MINN: Targeting Cognition and Motivation - National

This study is looking at whether psychoeducation can help people with depression, psychosis, or bipolarity. Participants receive a study treatment and complete follow-up visits and assessments.

SchizophreniaDeviceFrom 15 Years to 40 Years
Countries
United States
Sponsor
University of Minnesota
Condition
Schizophrenia
RecruitingNCT05837104

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolarity

This study is looking at whether Magnesium vitamin B6 can help people with Bipolarity I, Depression, Anxiety, or Stress. Participants take part in Magnesium vitamin B6 and complete follow-up assessments.

BipolarityDrugFrom 18 Years to 50 Years
Countries
United States
Sponsor
Mclean Hospital
Condition
Bipolarity
Not Yet RecruitingNCT06898879

Enhancing Veteran-Clinical Collaboration in VA PRRCs

This study is looking at whether a digital support tool can help people with depression, psychosis, or bipolarity. Participants take part in a digital support tool and complete follow-up assessments.

SchizophreniaBehavioralOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Schizophrenia
Depression | Clinical Trials | HopeStage Research