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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,345-1,356 of 7,264
Drug study icon
CompletedNCT04116528

Opiate Suicide Study in people with Major Depression

Official study title

Opiate Suicide Study in Patients With Major Depression

This study has finished and is no longer accepting participants.

In Stanford
DepressionMedication studyAges 18–70
Countries
United States
Sponsor
Stanford University
Drug study icon
CompletedNCT00223197

Pregnenolone study for Depression in Bipolarity or Recurrent Major Depressive Disorder With Substance Abuse

Official study title

A Double-blind Placebo Controlled Trial of Pregnenolone for Depression in Patients With Bipolar Disorders or Recurrent Major Depressive Disorder and a History of Substance Abuse

This study has finished and is no longer accepting participants.

In Dallas
Depression, BipolarityMedication studyAges 18–70
Countries
United States
Sponsor
University of Texas Southwestern Medical Center
Drug study icon
CompletedNCT06360419

Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol

What is this study about?

Researchers compared Solriamfetol 300 mg and placebo to find out how the approaches affected depression symptoms in people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Little Rock
DepressionMedication studyAges 18–65
Countries
United States
Sponsor
Axsome Therapeutics, Inc.
Drug study icon
TerminatedNCT00955474

Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms

Official study title

The Efficacy and Tolerability of Seroquel XR Combined With a Selective Serotonin Re-Uptake Inhibitor Versus Seroquel XR Monotherapy in the Acute Treatment of Major Depressive Disorder With Psychotic Features

This study ended early.

In Boston
Depression, SchizophreniaMedication studyAges 18–85
Countries
United States
Sponsor
Massachusetts General Hospital (Hospital / academic medical center)
Device study icon
UnknownNCT06443216

Sleep Modulation to Treat Depression

Official study title

Auditory Closed-loop Modulation of Slow Wave Sleep to Treat Major Depressive Disorder

Current recruitment status is unconfirmed.

In Geneva
DepressionDevice studyAges 30–60
Countries
Switzerland
Sponsor
Christoph Nissen
Drug study icon
TerminatedNCT04722666

MIJ821 for depression

Official study title

A Double-blind, Placebo-controlled, Randomized Dose-ranging Trial to Investigate Efficacy and Safety of Intravenous MIJ821 Infusion in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

This study ended early.

Multiple locations, including Birmingham
Depression, SuicidalityMedication studyAges 18–65
Countries
United States, Canada, Argentina, + 11 others
Sponsor
Novartis Pharmaceuticals
Drug study icon
CompletedNCT03726658

Zelquistinel in the Treatment of Adults With Major Depressive Disorder

What is this study about?

Researchers compared AGN-241751 and placebo to find out how the approaches affected depression symptoms in adults with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Phoenix
DepressionMedication studyAges 18–65
Countries
United States
Sponsor
Syndeio Biosciences, Inc

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.