Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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3928studies shown
Showing 2,901-2,925 of 3,928
OngoingEUCTR 2009-011911-19

Impact of quetiapine prolong and escitalopram on the hypothalamic-pituitary-adrenocortical (HPA)-axis activity in depressed patients

This study is comparing Seroquel Prolong 300 mg with Cipralex 10 mg for people with In this study, suffering from unipolar depression are investigated. 40 unipolar depressed inpatients enter the study after the procedure has been fully explained and written in.

DepressionOther
Countries
Germany
Sponsor
Ludwig-Maximilian-University of Munich, Department of Psychiatry
Condition
Depression
OngoingEUCTR 2016-001637-27

A randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression.

This study is comparing Quetiapine fumarate with Lithium carbonate for people with Treatment resistant depression. Treatment resistant depression, defined as failure to respond to two or more adequate doses of antidepressant in the cur or Elderly.

DepressionOther
Countries
United Kingdom
Sponsor
South London and Maudsley NHS Foundation Trust [...] 1. South London and Maudsley NHS Foundation Trust 2. King's College London
Condition
Depression
OngoingEUCTR 2010-022673-33

The Dexametasone-CRH-test as a potential predictor of treatment effect in depression: a pilot study.

This study is looking at whether CRH Ferring can help people with In total 40 subjects, aged 20-65 years, with depressive symptoms, considered by their physician to need antidepressant treatment, will be recruited from primary care clinics in the Stockholm area. Participants receive the study medicine CRH Ferring and complete study visits and assessments.

DepressionOther
Countries
Sweden
Sponsor
Psykiatri Nordväst, Karolinska Universitetssjukhuset Solna
Condition
Depression
OngoingEUCTR 2010-024364-18

The effects of ARA290 on the cognitive and neural processing of emotions in healthy volunteers

This study is looking at care and outcomes for people with emotional information processing. (Disease of interest is depression, however this trial is in or we will use a test battery that has previously been shown sensitive to the admin.

DepressionOther
Countries
Netherlands
Sponsor
Leiden University [...] 1. Leiden University 2. Leiden University Medical Center
Condition
Depression
OngoingEUCTR 2008-000041-60

Quetiapine in the treatment of psychotic depression. A pilot study (QTP-Dep-Bo)

This study is looking at whether Quetiapin can help people with The planned open and monocentric trial investigates quetiapine as a monotherapy for with unipolar depression and psychotic features. The aim of this pilot study is to investigate the antid.

DepressionOther
Countries
Germany
Sponsor
LWL Universitätsklinik für Psychiatrie Bochum
Condition
Depression
OngoingEUCTR 2013-001818-14

RELATE and PREDICT TRD A pharmacological and neuroimaging study investigating neurobiological effects of Selective Serotonin Reuptake Inhibitors and Norepinephrine Reuptake inhibitors on dopaminer...

This study is comparing Escitalopram 5mg (RVG 30494) Nortriptyline 10mg (RVG 03285) and 25mg (RVG 03286) with placebo for people with depression. Participants receive Escitalopram 5mg (RVG 30494) Nortriptyline 10mg (RVG 03285) and 25mg (RVG 03286) or placebo and complete study visits and assessments.

DepressionOther
Countries
Netherlands
Sponsor
University Medical Center Groningen
Condition
Depression
OngoingEUCTR 2022-000603-12

Oxytocin and reactivity to infant signals in mothers with postpartum depression

This study is comparing Syntocinon Nasal Spray with placebo for people with We examine the effects of oxytocin on mother-infant interaction among mothers with a postpartum depression. Participants receive Syntocinon Nasal Spray or placebo and complete study visits and assessments.

DepressionOther
Countries
Netherlands
Sponsor
Radboud University
Condition
Depression
OngoingEUCTR 2020-000469-18

A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients

This study is comparing IP2018 with placebo for people with Male with a diagnosis of mild to moderate depression and ED as determined from the Hamilton depression scale score of 7 to 23 and International Index of Erectile Function score of. Participants receive IP2018 or placebo and complete study visits and assessments.

DepressionOther
Countries
United Kingdom
Sponsor
Initiator Pharma
Condition
Depression
OngoingEUCTR 2006-005531-17

Xenon als Antidepressivum

This study is comparing Xenon pro Anaesthesia with placebo for people with depression and recurrent mayor depression or Elderly. Participants receive Xenon pro Anaesthesia or placebo and complete study visits and assessments.

DepressionOther
Countries
Germany
Sponsor
Klinik für Anästhesiologie Universitätsklinikum Aachen
Condition
Depression
OngoingEUCTR 2018-002942-35

A Randomised Controlled Trial of Escitalopram and Nortriptyline compared with placebo and standard psychological care for depression in Parkinson’s Disease

This study is comparing Escitalopram oxalate with placebo for people with Depression in Parkinson's disease or Elderly. Participants receive Escitalopram oxalate or placebo and complete study visits and assessments.

DepressionOther
Countries
United Kingdom
Sponsor
University College London Comprehensive Clinical Trials Unit
Condition
Depression
OngoingEUCTR 2005-005266-37

Influence of Escitalopram on the incidence of depression and dementia following acute middle cerebral artery territory infarction. A randomized, placebo-controlled, double blind study.

This study is comparing Escitalopram with placebo for people with Acute territorial infarction in the territory of the middle cerebral artery or Elderly. Participants receive Escitalopram or placebo and complete study visits and assessments.

DepressionOther
Countries
Germany
Sponsor
Central Institute for Mental Health, Mannheim, Div. of Gerontopsychiatry
Condition
Depression
OngoingEUCTR 2019-001023-13

PAX-D: Randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression

This study is comparing Pramipexole dihydrochloride monohydrate with placebo for people with Treatment resistant depression or Elderly. Participants receive Pramipexole dihydrochloride monohydrate or placebo and complete study visits and assessments.

DepressionOther
Countries
United Kingdom
Sponsor
University of Oxford / Clinical Trials and Research Governance
Condition
Depression
OngoingEUCTR 2008-000453-35

Open-label phase IIa pilot study exploring safety and potential efficacy of recombinant human erythropoietin in early mild Alzheimer Dementia and therapy-refractory Major Depression (“EPO-AD”)

This study is comparing Epoetin alfa with placebo for people with Early, mild dementia of the Alzheimer’s Type and therapy-refractory Major Depression or Elderly. Participants receive Epoetin alfa or placebo and complete study visits and assessments.

DepressionOther
Countries
Germany
Sponsor
Max-Planck-Institute of Experimental Medicine
Condition
Depression
OngoingEUCTR 2019-001683-29

Double-Blind, Placebo-Controlled, Multi-Center Study Investigating the Efficacy, Safety, and Tolerability of JNJ-61393215 as Adjunctive Treatment in Adults with Major Depressive Disorder with Anxio...

This study is comparing N/A with placebo for people with Adjunctive Treatment in with depression with Anxious Distress with Suboptimal Response to Standard Antidepressants. Participants receive N/A or placebo and complete study visits and assessments.

DepressionOther
Countries
United Kingdom
Sponsor
Janssen-Cilag International NV
Condition
Depression
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