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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,441-1,452 of 7,264
Behavioral study icon
Not Yet RecruitingNCT07176637

A-B-C Program for Sedentary Older Adults With Depressive Symptoms

Official study title

A-B-C Program: a Brief Intervention to Promote an Active Lifestyle by Addressing Behavioral Economics Cognitive Biases Among Sedentary Older Adults With Depressive Symptoms-a Randomized Controlled Trial

This study isn't recruiting yet.

Location not clearly listed
DepressionBehavioural studyAges 65+
Countries
Sponsor
The Royal Ottawa Mental Health Centre
Drug study icon
WithdrawnNCT03852160

Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant for treatment-resistant depression

Official study title

A Randomized, Double-Blind, Active-Controlled, International, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Flexibly-dosed Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

This study was withdrawn before enrollment.

Location not clearly listed
DepressionMedication studyAges 18–74
Countries
Sponsor
Janssen-Cilag International NV
Drug study icon
CompletedNCT04599855

Esketamine Nasal Spray, Administered for treatment-resistant depression

Official study title

A Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18+
Countries
United States
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT02493868

Intranasal Esketamine Plus an Oral Antidepressant for treatment-resistant depression

Official study title

A Randomized, Double-blind, Multicenter, Active-Controlled Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–64
Countries
United States, France, Canada, + 12 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT01627782

Ketamine for treatment-resistant depression

Official study title

A Double-blind, Randomized, Placebo-controlled, Parallel Group, Dose Frequency Study of Ketamine in Subjects With Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–64
Countries
United States
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT01640080

Efficacy of Intravenous Esketamine for treatment-resistant depression

What is this study about?

This study evaluated the effectiveness of Esketamine for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Dave
DepressionMedication studyAges 18–64
Countries
Belgium, Germany, Poland
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT03434041

Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant for treatment-resistant depression

Official study title

A Randomized, Double-blind, Multicenter Active-controlled Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Subjects With Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Atlanta
DepressionMedication studyAges 18–64
Countries
United States, China
Sponsor
Janssen Research & Development, LLC

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.