Get research updatesDepression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.
This study evaluated the safety and effectiveness of BPL-003 for people with depression.
This study has finished and is no longer accepting participants.
Multiple locations, including Birmingham
Deep Brain Stimulation for Treatment Resistant Depression: Exploration of Local Field Potentials (LFP) With the Medtronic Activa Primary Cell + Sensing (PC+S) "Brain Radio" System
This study is no longer accepting new participants.
In AtlantaTargeting mTOR/GSK3 With Lithium Augmentation to Enhance and Sustain Rapid Antidepressant Actions of Ketamine in Adults With Treatment-Resistant Depression: A Precision Medicine Approach for Psychiatry
This study was withdrawn before enrollment.
In RochesterA Pilot Safety and Efficacy Study of Epidural Prefrontal Cortical Stimulation (EpCS) in Severe Treatment Resistant Depression
This study is no longer accepting new participants.
In Charleston
Aerobic Exercise to Augment the Plasticity Effect of rTMS in Patients With Treatment-resistant Depression
This study has finished and is no longer accepting participants.
In ProvidenceFunctional Magnetic Resonance Imaging of Patients Receiving Intravenous Ketamine for Treatment Resistant Bipolar Depression
This study has finished and is no longer accepting participants.
Multiple locations, including ClevelandHome-based Transcranial Direct Current Stimulation (tDCS) for Treatment Resistant Depression: a Randomized Clinical Trial
Current recruitment status is unconfirmed.
In Porto AlegreIntensive Accelerated Intermittent Theta Burst Stimulation in Treatment-resistant Depression: A Multicenter, Randomized, Double-blind, Placebo Parallel Controlled Trial
This study has finished and is no longer accepting participants.
Multiple locations, including BaodingMedication-assisted Psychotherapy: Using Ketamine-enhanced Radically Open Dialectical Behavior Therapy (RO DBT) to Target Neural and Behavioral Mechanisms of Action in Adults With Moderate to Severe Depression
This study has finished and is no longer accepting participants.
In St LouisThis study assessed depression symptoms.
This study has finished and is no longer accepting participants.
In TorontoAmygdala rtfMRI Neurofeedback for Treatment Resistant Depression
This study has finished and is no longer accepting participants.
In PittsburghPersonalized Brain Functional Sectors (pBFS) Guided High-dose rTMS Therapy for Treatment-resistant Depression: A Randomized, Double-Blind, Sham-controlled Trial
Recruitment is currently suspended.
In BeijingWe gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.