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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,861-1,872 of 7,264
Biological study icon
Active Not RecruitingNCT05174273

Neurocognitive Effects of FMT in MDD people with and Without IBS

Official study title

Understanding the Neurocognitive Effects of Fecal Microbiota Transplantation in Major Depressive Disorder Patients With and Without Irritable Bowel Syndrome

This study is no longer accepting new participants.

In Calgary
DepressionInterventional studyAges 18–60
Countries
Canada
Sponsor
Valerie Taylor
Device study icon
SuspendedNCT06112652

Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique

Official study title

The Dosage Effect of Personalized Brain Functional Sectors(pBFS) Guided rTMS Treatment for Treatment-resistance Depression: a Randomized, Double-Blind, Sham-controlled Trial

Recruitment is currently suspended.

In Wuhan
DepressionDevice studyAges 18–65
Countries
China
Sponsor
Changping Laboratory
Other study type icon
CompletedNCT05065580

OMT as an Adjunctive Treatment in MDD

Official study title

Osteopathic Manipulative Treatment as an Adjunctive Treatment in Major Depressive Disorder

This study has finished and is no longer accepting participants.

In Saint Joseph
DepressionInterventional studyAges 18–65
Countries
United States
Sponsor
Corewell Health South
Behavioral study icon
Enrolling By InvitationNCT05935644

ORCHID: An Online Intervention for Persons With HIV (Miami)

Official study title

ORCHID: A Novel Positive Affect Intervention for Aging, Racial/Ethnic Minoritized Women With HIV (Miami)

This study is by invitation only.

In Miami
DepressionBehavioural studyAges 18–90
Countries
United States
Sponsor
University of Miami
Drug study icon
CompletedNCT06391593

PD, PK, and Safety of ALTO-203 in people with MDD

Official study title

Double-Blind, Single and Multiple Dose Study to Determine Pharmacodynamic Markers, Pharmacokinetic Parameters, and Safety of ALTO-203 in Patients With Major Depressive Disorder

This study has finished and is no longer accepting participants.

Multiple locations, including Tucson
DepressionMedication studyAges 25–64
Countries
United States
Sponsor
Alto Neuroscience
Drug study icon
CompletedNCT05712187

Phase 2b Study of ALTO-100 in MDD

What is this study about?

Researchers compared ALTO-100 and placebo to find out how the approaches affected depression symptoms in adults with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–64
Countries
United States
Sponsor
Alto Neuroscience
Drug study icon
SuspendedNCT06705478

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Official study title

An Open-Label, Randomized Controlled Trial of Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Recruitment is currently suspended.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–70
Countries
United States, Botswana, Brazil, + 11 others
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Drug study icon
TerminatedNCT06011577

Study of REL-1017 as Adjunctive Treatment for MDD

Official study title

A Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as an Adjunctive Treatment for Major Depressive Disorder (RELIGHT)

This study ended early.

Multiple locations, including Dothan
DepressionMedication studyAges 18–65
Countries
United States
Sponsor
Levomecor Inc.
Drug study icon
CompletedNCT04032301

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

Official study title

Characterization of Comorbid Post-traumatic Stress Disorder and Major Depressive Disorder Utilizing Ketamine as an Experimental Medicine Probe

This study has finished and is no longer accepting participants.

In Minneapolis
Depression, PTSDMedication studyAges 18–75
Countries
United States
Sponsor
University of Minnesota
Other study type icon
TerminatedNCT01310140

Risks for Insulin Resistance and Metabolic Syndrome Between Major Depressive Disorder (MDD) or MDD With Psychotic Features

Official study title

Comparative Risks for Insulin Resistance and Metabolic Syndrome (MS) Among Hospitalized Patients With Major Depressive Disorder With (MDpsy) or Without (MDD) Psychotic Features

This study ended early.

In Boston
Depression, SchizophreniaObservational studyAges 18–85
Countries
United States
Sponsor
Massachusetts General Hospital (Hospital / academic medical center)
Device study icon
CompletedNCT06126198

RTMS Feasibility Study on Adolescent Depression Stimulation

Official study title

1 Hz RTMS Feasibility Study on Adolescent Treatment Resistant Major Depression

This study has finished and is no longer accepting participants.

In Uppsala
Depression, BipolarityDevice studyAges 13–19
Countries
Sweden
Sponsor
Uppsala University

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.