RecruitingNCT07493317
Neutralizing Interleukin (IL)-6
Official study title
In New YorkNeutralizing Interleukin (IL)-6 Signaling to Reverse Immune Related Anhedonia in Patients With Major Depressive Disorder
DepressionMedication studyAges 18–70
Study directory
Back to overviewDepression studies
Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.
RecruitingNCT05136755
NMDA Modulation in Antidepressant Nonresponders With Major Depressive Disorder
In TaichungDepressionMedication studyAges 18–65
RecruitingNCT04637620
NMDA Modulation in Major Depressive Disorder
In TaichungDepressionMedication studyAges 18–55
RecruitingNCT07490782
Nutritional Intervention for College Students With Depression
In La JollaDepressionBehavioural studyAges 18+
RecruitingNCT07242105
Optimizing Brain Excitability in Depression
Official study title
Multiple locations, including Iowa CityOptimized Methods for Measuring Brain Excitability in Depression
DepressionDevice studyAges 18–65
RecruitingNCT06610305
Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression
Official study title
In Chapel HillOvarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression: A Crossover Randomized Controlled Trial
DepressionMedication studyAges 18–45
RecruitingNCT07113548
PERSONAE - a Personalized Online Treatment of Depression
Official study title
In OdensePERSONAE: a Personalized Adaptation of Stepped Care Internet-based Cognitive Behavioral Therapy for Depression - A Randomized Controlled Trial
DepressionBehavioural studyAges 18+
RecruitingNCT06784388
Personalized DBS Targeting for Treating Depression
Official study title
In HangzhouClinical Application of Personalized DBS Target Optimization for Treating Depression
DepressionMedication studyAges 18–70
RecruitingNCT06410599
Pharmacologic Treatment Augmentation in Chronic Depression
Official study title
Multiple locations, including TübingenPharmacologic Treatment Augmentation in Chronic Depression "Randomized, Controlled, Double Blinded, Phase II Study"
DepressionMedication studyAges 18–64
RecruitingNCT06103760
Positioning of Esketamine Treatment in the Real-world Management of Depression
In St LeonardsDepressionMedication studyAges 18–65
RecruitingNCT05866575
Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation
Official study title
In ParisPrediction of the Therapeutic Response in Depression Based on an Early Neuro-computational Modeling Assessment of Motivation
DepressionInterventional studyAges 18+
RecruitingNCT06878859
Preliminary Efficacy study of a Digital Intervention for Depression and Cannabis Use
Official study title
In BostonAMP-C: A Digital Therapeutic for Reward Dysfunction in Co-Occurring Depression and Cannabis Use
Depression, AddictionBehavioural studyAges 18+
Registry coverage
We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.