HopeStage
Study directory

Depression studies

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

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7264studies shown
Showing 481-492 of 7,264
Device study icon
RecruitingNCT06038929

Digestion after vagus nerve stimulation for treatment-resistant depression

About this title

Effect of Vagal Nerve Stimulation on Gastric Motor Functions

Read the official source — NCT06038929
Official study title

REVEAL - Research Evaluating Vagal Excitation and Anatomical Linkages Gastric Emptying Ancillary Project: Effect of Vagal Nerve Stimulation on Gastric Motor Functions

Multiple locations, including Minneapolis
DepressionDevice studyAges 18+
Countries
United States
Sponsor
Mayo Clinic
Behavioral study icon
RecruitingNCT06480019

Group interpersonal therapy or waiting list for young adults with depression in Brazil

About this title

IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil

Read the official source — NCT06480019
Official study title

IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil: a Randomized Clinical Trial

In Porto Alegre
DepressionBehavioural studyAges 18–24
Countries
Brazil
Sponsor
Hospital de Clinicas de Porto Alegre
Behavioral study icon
RecruitingNCT05691439

Sleep extension and depressive symptoms in adolescents

About this title

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

Read the official source — NCT05691439
Official study title

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep Duration and Timing to Reward- and Stress-Related Brain Function

In Eugene
DepressionBehavioural studyAges 14–18
Countries
United States
Sponsor
University of Oregon
Drug study icon
RecruitingNCT06782724

Psilocybin and depressive symptoms in people with serious physical illnesses

About this title

Psilocybin Therapy for Psychological Distress in Palliative Patients

Read the official source — NCT06782724
Official study title

The Safety and Efficacy of Psilocybin Therapy Compared to Low-dose Control in Reducing Depressive Symptoms in Patients With COPD, ALS, MS, or APD.

Multiple locations, including Prague
DepressionMedication studyAges 18+
Countries
Czechia, Denmark, Netherlands, + 1 other
Sponsor
University Medical Center Groningen
Device study icon
RecruitingNCT06719427

EEG brain activity during magnetic stimulation for treatment-resistant depression

About this title

qEEG Brain Signature of Depression & Neuromodulation-induced Recovery

Read the official source — NCT06719427
Official study title

Quantitative Electroencephalography to Longitudinally Assess the Functional Brain Signature of Treatment-resistant Depression and Recovery With Therapeutic Neuromodulation

In Toronto
DepressionDevice studyAges 18–80
Countries
Canada
Sponsor
Sunnybrook Health Sciences Centre
Drug study icon
RecruitingNCT05851898

Pilot study of duloxetine and depressive symptoms after fragility fractures

About this title

Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures

Read the official source — NCT05851898
Official study title

The Role of SNRI's in the Prophylaxis of Depression in the First Year Following Lower Extremity Fragility Fractures in Geriatric Patients

In Winston-Salem
DepressionMedication studyAges 65+
Countries
United States
Sponsor
Wake Forest University Health Sciences
Drug study icon
CompletedNCT06570369

A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression

Official study title

A Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Study to Explore the Effect of SP-624 on Brain Network Analytics in Cohorts of Healthy Adult Subjects and Subjects With Major Depressive Disorder

This study has finished and is no longer accepting participants.

Multiple locations, including Garden Grove
DepressionMedication studyAges 18–60
Countries
United States
Sponsor
Sirtsei Pharmaceuticals, Inc.

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.