Neural Response to Inflammatory Challenge in Major Depressive Disorder
This study is comparing LPS with placebo for people with depression. Participants receive LPS or placebo and complete study visits and assessments.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.
This study is comparing LPS with placebo for people with depression. Participants receive LPS or placebo and complete study visits and assessments.
This study is looking at compare the antidepressant effects of propofol at two different doses while measuring potential treatment-related biomarkers for people with Treatment Resistant Depression. Participants receive a study treatment and complete follow-up visits and assessments.
This study is looking at care and outcomes for people with Cannabis Use or Depression. Taking part may give some people access to Neuroimaging Investigation, but direct benefit is not guaranteed.
This study is looking at care and outcomes for people with depression. Taking part may give some people access to Genetic testing with regular follow-up, but direct benefit is not guaranteed.
This study is looking at explore the potential impact of maternal neuraxial labor analgesia exposure on offspring neurodevelopment for people with depression. Participants are followed over time so researchers can learn from clinical and follow-up information.
This study is looking at whether questionnaires and follow-up can help people with Depression in Adolescence or Depression in. Participants receive a study treatment and complete follow-up visits and assessments.
This study is looking at determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression for people with depression, anxiety or depression, or Hiv. Participants receive Placebo or placebo and complete study visits and assessments.
This study is looking at whether Neurobehavioral therapy can help people with depression or Epilepsy. Participants take part in Neurobehavioral therapy and complete follow-up assessments.
This study is looking at whether an online mindfulness program can help people with Sleep Disturbances or Depression. Participants take part in an online mindfulness program and complete follow-up assessments.
This observational study is following people with depression or Rumination to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.
This observational study is following people with Healthy or depression to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.
This study is looking at whether a digital support tool can help people with Depression. Participants receive a study treatment and complete follow-up visits and assessments.
This study is looking at care and outcomes for people with Depression or Treatment Resistant Depression. Taking part may give some people access to Repetitive Transcranial Magnetic Stimulation, but direct benefit is not guaranteed.
This study is comparing Lumateperone 42 mg with placebo for people with Major Depressive Diorder or Early Life Trauma. Participants receive Lumateperone 42 mg or placebo and complete study visits and assessments.
This study is looking at care and outcomes for people with depression or Irritable Bowel Syndrome. Some participants may receive Healthy Controls instead of the study treatment, and direct benefit is not guaranteed.
This observational study is following people with Food Insecurity, Depression, or Anxiety to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.
This study is comparing fNIRS with Sham Group for people with Depression, Anxiety. Participants receive fNIRS or Sham Group and complete study visits and assessments.
This study is comparing Active Closed Loop Real Time fMRI Neurofeedback with Sham Comparator: Sham Neurofeedback for people with depression. Participants receive Active Closed Loop Real Time fMRI Neurofeedback or Sham Comparator: Sham Neurofeedback and complete study visits and assessments.
This study is looking at whether cognitive behavioural therapy can help people with depression. Participants receive a study treatment and complete follow-up visits and assessments.
This observational study is following people with major depression to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.
This study is looking at whether a digital support tool can help people with depression. Participants receive a study treatment and complete follow-up visits and assessments.
This study is looking at whether a digital support tool can help people with Major Depression Disorder, Cognitive Deficits, or Selective Attention. Participants take part in a digital support tool and complete follow-up assessments.
This study is looking at care and outcomes for people with Neuropathic Pain or Depression. Taking part may give some people access to Repetitive transcranial magnetic stimulation (rTMS) - M1/DLPFC, but direct benefit is not guaranteed.
This study is looking at care and outcomes for people with Old Age or depression, Treatment-Resistant. Some participants may receive Sham adTMS instead of the study treatment, and direct benefit is not guaranteed.
This study is comparing 4 session rTMS with sham rTMS for people with Moderate Depression, depression, or Severe Depression. Participants receive 4 session rTMS or sham rTMS and complete study visits and assessments.