Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

Back to overview
2022studies shown
Showing 801-825 of 2,022
OngoingEUCTR 2005-003156-35

Efficacy and tolerability of Ziprasidone vs. Clozapine in the treatment of dually diagnosed (DD-) patients with schizophrenia and cannabis use disorder: A randomised study

This study is comparing Ziprasidon with Clozapine for people with with schizophrenia and cannabis abuse/dependency will be randomized to ziprasidone or clozapine treatment. Dose of medication and frequency of administration will be flexible and adjustab.

SchizophreniaOther
Countries
Germany
Sponsor
Department of Psychiatry and Psychotherapy (Cologne)
Condition
Schizophrenia
OngoingEUCTR 2008-005019-16

Randomized Olanzapine Clozapine Key study on Schizophrenia and Addiction in the Netherlands (ROCKSAN)

This study is comparing CLOZAPINE with OLANZAPINE for people with A multi-centre prospective, randomized, double blind designed study examining the effectiveness and costs of clozapine compared to olanzapine in with schizophrenia or related psychotic dis. Participants receive CLOZAPINE or OLANZAPINE and complete study visits and assessments.

SchizophreniaOther
Countries
Netherlands
Sponsor
AMC- academisch psychiatrisch centrum
Condition
Schizophrenia
OngoingEUCTR 2008-003623-23

Effect of different antipsychotic medication on craving related brain activity in patients with schizophrenia and cannabis abuse or dependence: a randomized controlled study comparing clozapine and...

This study is looking at whether CLOZAPINE compared with RISPERIDONE can help people with A randomized controlled trial comparing the effect of clozapine and risperidone on cannabis craving in cannabis abusing or dependent with schizophrenia. Specific cognitive tasks will be us.

SchizophreniaOther
Countries
Netherlands
Sponsor
Academisch medisch centrum, department of psychiatry
Condition
Schizophrenia
OngoingEUCTR 2022-001582-12

Open, multicenter, randomized clinical trial to evaluate the efficacy and safety of aripiprazole vs paliperidone / risperidone using multi-omics data in patients with a first psychotic episode.

This study is comparing Abilify Maintena with Xeplion for people with First episode SZ-spectrum individuals or Adolescents, Under 18. Participants receive Abilify Maintena or Xeplion and complete study visits and assessments.

SchizophreniaOther
Countries
Spain
Sponsor
Consorcio Centro de Investigacion Biomedica en Red (CIBER)
Condition
Schizophrenia
CompletedEUCTR 2020-006062-36

A PHASE II/III, PROSPECTIVE, MULTI-CENTER, RANDOMIZED, 4-WEEK, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY, DESIGNED TO DETERMINE THE SAFETY, TOLERABILITY, EEG EFFECTS AND EFFICACY OF ORAL DOSES OF 30 M...

This study is comparing Evenamide with placebo for people with Chronic schizophrenia or Elderly. Participants receive Evenamide or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
Germany, Italy, Czech Republic, Spain, Romania, Hungary, Poland, Estonia, Latvia, View results
Sponsor
Newron Pharmaceuticals S.p.A.
Condition
Schizophrenia
OngoingEUCTR 2013-005399-16

Randomized, flexible-dose, open-label comparison to investigate the effectivenes of second generation antipsychotics in first episode psychosis patients.

This study is looking at whether ARIPIPRAZOLE compared with RISPERIDONE can help people with First episode drug-naïve of psychosis. Participants receive one of the study medicines, such as ARIPIPRAZOLE or RISPERIDONE, and complete study visits and assessments.

SchizophreniaOther
Countries
Spain
Sponsor
Dr. Benedicto Crespo. Servicio Psiquiatría. Hospital Universitario Marqués de Valdecilla/IDIVAL
Condition
Schizophrenia
CompletedEUCTR 2017-001447-12

A Multicenter, Randomized, Double-blind, Placebo- and Active controlled Trial to Evaluate the Efficacy of Brexpiprazole Monotherapy for the Treatment in Adolescents (13-17 years old) With Schizophr...

This study is comparing Brexpiprazole with placebo for people with Schizophrenia or Adolescents, Under 18. Participants receive Brexpiprazole or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
Hungary, Spain, Poland, Bulgaria, France, Italy, Romania, View results
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Condition
Schizophrenia
CompletedEUCTR 2019-003343-29

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia (ADVANCE 2)

This study is comparing Pimavanserin with placebo for people with Schizophrenia. Participants receive Pimavanserin or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
Czech Republic, Poland, Hungary, Bulgaria, Spain, Lithuania, Italy, Croatia, View results
Sponsor
ACADIA Pharmaceuticals Inc.
Condition
Schizophrenia
OngoingEUCTR 2007-004857-27

Ventral striatal function in patients with schizophrenia before and under medication with atypical antipsychotics: a comparison of sertindole and risperidone

This study is looking at whether Sertindol compared with Risperidon can help people with schizophrenic and healthy controls. Participants receive one of the study medicines, such as Sertindol or Risperidon, and complete study visits and assessments.

SchizophreniaOther
Countries
Germany
Sponsor
Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich
Condition
Schizophrenia
OngoingEUCTR 2020-003745-11

An open label, single arm, extension trial to examine long-term safety of BI 425809 once daily in patients with schizophrenia who have completed previous BI 425809 Phase III trials.(CONNEX-X)

This study is looking at whether None yet can help people with Schizophrenia. Participants receive the study medicine None yet and complete study visits and assessments.

SchizophreniaOther
Countries
France, Czech Republic, Spain, Slovakia, Hungary, Norway, Denmark, Lithuania, Italy, Greece, Belgium, Sweden, Netherlands, Finland, Croatia, Austria, Bulgaria, Portugal, Romania
Sponsor
Boehringer Ingelheim
Condition
Schizophrenia
OngoingEUCTR 2012-005435-87

EFFECT OF ADJUVANT TREATMENT WITH N - ACETYLCYSTEINE DURING 48 WEEKS ON THE LOSS OF GREY SUBSTANCE AND OXIDATIVE METABOLISM IN PATIENTS WITH EARLY ONSET PSYCHOTIC EPISODES: BLIND, PLACEBO-CONTROLLE...

This study is comparing ACETYLCYSTEINE with placebo for people with with early onset psychotic episodes or Adolescents, Under 18. Participants receive ACETYLCYSTEINE or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
Spain
Sponsor
Fundación para la Investigación Biomédica Hospital Gregorio Marañón
Condition
Schizophrenia
OngoingEUCTR 2016-004973-42

A phase II randomised, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered BI 409306 during a 52-week treatment period as an early inter...

This study is looking at care and outcomes for people with attenuated psychosis syndrome or Adolescents, Under 18. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

SchizophreniaOther
Countries
United Kingdom, View results
Sponsor
Boehringer Ingelheim Limited
Condition
Schizophrenia
OngoingEUCTR 2016-000118-31

A randomised phase II double-blinded placebo-controlled trial of intravenous immunoglobulins and rituximab in patients with antibody-associated psychosis (SINAPPS2)

This study is comparing Human normal immunoglobulin with placebo for people with Antibody associated Psychosis or Elderly. Participants receive Human normal immunoglobulin or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
United Kingdom
Sponsor
Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
Condition
Schizophrenia
OngoingEUCTR 2019-003623-37

CANnabidiol for Parkinson’s Disease Psychosis

This study is comparing Cannabidiol (CBD) with placebo for people with Parkinson's disease psychosis or Elderly. Participants receive Cannabidiol (CBD) or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
United Kingdom
Sponsor
King's College London [...] 1. King's College London 2. South London and Maudsley NHS Foundation Trust
Condition
Schizophrenia
CompletedEUCTR 2015-003503-39

Placebo-controlled Trial in Subjects at Ultra-high Risk for Psychosis With Omega-3 Fatty Acids in Europe

This study is looking at care and outcomes for people with Individuals at Ultra High Risk for Psychosis or Adolescents, Under 18. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

SchizophreniaOther
Countries
Netherlands, Austria, Italy, Spain, Germany, United Kingdom
Sponsor
University Medical Center Utrecht
Condition
Schizophrenia
OngoingEUCTR 2022-001515-10

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Relapse Prevention Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated with Alzheimer’s Disease Deme...

This study is comparing Trospium chloride with placebo for people with Psychosis Associated with Alzheimer’s Disease Dementia or Elderly. Participants receive Trospium chloride or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
Spain, Slovakia, France, Italy, Bulgaria, Germany
Sponsor
Karuna Therapeutics
Condition
Schizophrenia
OngoingEUCTR 2017-002227-13

A Double-blind, Placebo-controlled, Relapse Prevention Study of Pimavanserin for the Treatment of Hallucinations and Delusions Associated With Dementia-related Psychosis

This study is comparing Pimavanserin with placebo for people with Hallucinations and Delusions Associated With Dementia-related Psychosis or Elderly. Participants receive Pimavanserin or placebo and complete study visits and assessments.

SchizophreniaOther
Countries
United Kingdom, Czech Republic, Slovakia, Bulgaria, Spain, Poland, France, Italy, View results
Sponsor
ACADIA Pharmaceuticals Inc.
Condition
Schizophrenia
CompletedNCT07549581

A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode

This study assessed the safety and pharmacology of SEP-380135 in adults living with schizophrenia or a major depressive episode linked to bipolarity or major depressive disorder. The registry now lists the study as completed.

DepressionOtherFrom 18 Years to 55 Years
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Condition
Depression
OngoingEUCTR 2021-004049-19

Sodium oxybate as a potential new treatment for catatonia in patients with depression, bipolarity or a psychotic disorder, a randomized controlled trial. The Laborit study.

This EU CTR study is testing sodium oxybate for catatonia in adults living with depression, bipolarity, or psychotic disorders. The registry page currently marks the Dutch protocol as transitioned, which the app maps to ongoing.

DepressionOther
Countries
Netherlands
Sponsor
Amsterdam UMC
Condition
Depression