Schizophrenia
Schizophrenia can affect how a person perceives reality, thinks and feels, sometimes involving hearing voices or holding unusual beliefs.
CompletedNCT05628103
What is this study about?Researchers studied SEP-363856, tracking side effects to assess safety and tolerability in people with schizophrenia.
This study has finished and is no longer accepting participants.
Multiple locations, including AnaheimSchizophreniaMedication studyAges 18–65
- Countries
- United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
TerminatedNCT04109950
What is this study about?Researchers are studying SEP-363856, tracking side effects to assess safety and tolerability in people with schizophrenia.
This study ended early.
Multiple locations, including Little RockSchizophreniaMedication studyAges 13–65
- Countries
- United States, Bulgaria, Colombia, + 5 others
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT04038957
Official study titleAn Open-Label Positron Emission Tomography Study to Investigate the Effect of Adjunctive Administration of SEP-363856 on Brain Dopamine Synthesis Capacity Using 18F-DOPA in Adult Subjects With Schizophrenia
This study has finished and is no longer accepting participants.
In LondonSchizophreniaMedication studyAges 18–45
- Countries
- United Kingdom
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT04369391
Official study titleA Randomized, Single-dose, Crossover Study of the Effects of SEP-363856 on Electrocardiogram (ECG) Intervals in Subjects With Schizophrenia
This study has finished and is no longer accepting participants.
Multiple locations, including Little RockSchizophreniaMedication studyAges 18–65
- Countries
- United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT05848700
Official study titleA Double-Blind, Placebo-Controlled, Randomized Withdrawal Study to Evaluate SEP-363856 Physical Dependence in Adult Subjects With Schizophrenia
This study has finished and is no longer accepting participants.
Multiple locations, including Little RockSchizophreniaMedication studyAges 18–65
- Countries
- United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT04865835
Official study titleA Randomized, Single-blind, Two-period Crossover to Investigate the Effect of SEP-363856 on the Pharmacokinetics of Metformin in Subjects With Schizophrenia.
This study has finished and is no longer accepting participants.
Multiple locations, including Oakland ParkSchizophreniaMedication studyAges 18–65
- Countries
- United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT04092686
What is this study about?Researchers compared SEP-363856 75mg, SEP-363856 100mg and placebo to find out how the approaches affected psychotic symptoms in people with schizophrenia.
This study has finished and is no longer accepting participants.
Multiple locations, including RogersSchizophreniaMedication studyAges 18–65
- Countries
- United States, Bulgaria, Croatia, + 4 others
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
CompletedNCT06356389
What is this study about?This study evaluated the safety of JX11502MA for people with schizophrenia.
This study has finished and is no longer accepting participants.
In ShanghaiSchizophreniaMedication studyAges 18–55
- Countries
- China
- Sponsor
- Zhejiang Jingxin Pharmaceutical Co., Ltd.
TerminatedNCT04825860
What is this study about?Researchers are comparing SEP-363856 50 mg, SEP-363856 75 mg and placebo to find out how the approaches affect psychotic symptoms in people with schizophrenia.
This study ended early.
Multiple locations, including BeijingSchizophreniaMedication studyAges 18–65
- Countries
- China, Japan, Philippines, + 1 other
- Sponsor
- Sumitomo Pharma Co., Ltd.
TerminatedNCT05359081
What is this study about?Researchers are studying SEP-363856, tracking side effects to assess long-term safety and tolerability in people with schizophrenia.
This study ended early.
Multiple locations, including Konan-shiSchizophreniaMedication studyAges 18–65
- Countries
- Japan
- Sponsor
- Sumitomo Pharma Co., Ltd.
CompletedNCT04072354
What is this study about?Researchers compared SEP-363856 50mg, SEP-363856 75mg and placebo to find out how the approaches affected psychotic symptoms in people with schizophrenia.
This study has finished and is no longer accepting participants.
Multiple locations, including Little RockSchizophreniaMedication studyAges 13–65
- Countries
- United States, Bulgaria, Colombia, + 3 others
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
TerminatedNCT01328093
Official study titleA Phase 3, Multicenter, Double-Blind Comparison of LY2140023 and Aripiprazole in Patients With DSM-IV-TR Schizophrenia Followed by Open-Label Treatment With LY2140023
This study ended early.
Multiple locations, including CerritosSchizophreniaMedication studyAges 18–65
- Countries
- United States, France, Belgium, + 6 others
- Sponsor
- Denovo Biopharma LLC