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Schizophrenia

Schizophrenia can affect how a person perceives reality, thinks and feels, sometimes involving hearing voices or holding unusual beliefs.

4505studies shown
Showing 937-948 of 4,505
Drug study icon
CompletedNCT05628103

A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication

What is this study about?

Researchers studied SEP-363856, tracking side effects to assess safety and tolerability in people with schizophrenia.

This study has finished and is no longer accepting participants.

Multiple locations, including Anaheim
SchizophreniaMedication studyAges 18–65
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
TerminatedNCT04109950

Safety study of investigational Drug in schizophrenia

What is this study about?

Researchers are studying SEP-363856, tracking side effects to assess safety and tolerability in people with schizophrenia.

This study ended early.

Multiple locations, including Little Rock
SchizophreniaMedication studyAges 13–65
Countries
United States, Bulgaria, Colombia, + 5 others
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
CompletedNCT04038957

A Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychotic, in Adults With Schizophrenia, as Measured Positron Emission Tomography (PET) Imaging

Official study title

An Open-Label Positron Emission Tomography Study to Investigate the Effect of Adjunctive Administration of SEP-363856 on Brain Dopamine Synthesis Capacity Using 18F-DOPA in Adult Subjects With Schizophrenia

This study has finished and is no longer accepting participants.

In London
SchizophreniaMedication studyAges 18–45
Countries
United Kingdom
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
CompletedNCT04369391

A Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults With Schizophrenia.

Official study title

A Randomized, Single-dose, Crossover Study of the Effects of SEP-363856 on Electrocardiogram (ECG) Intervals in Subjects With Schizophrenia

This study has finished and is no longer accepting participants.

Multiple locations, including Little Rock
SchizophreniaMedication studyAges 18–65
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
CompletedNCT05848700

A Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With Schizophrenia

Official study title

A Double-Blind, Placebo-Controlled, Randomized Withdrawal Study to Evaluate SEP-363856 Physical Dependence in Adult Subjects With Schizophrenia

This study has finished and is no longer accepting participants.

Multiple locations, including Little Rock
SchizophreniaMedication studyAges 18–65
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
CompletedNCT04865835

A study Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

Official study title

A Randomized, Single-blind, Two-period Crossover to Investigate the Effect of SEP-363856 on the Pharmacokinetics of Metformin in Subjects With Schizophrenia.

This study has finished and is no longer accepting participants.

Multiple locations, including Oakland Park
SchizophreniaMedication studyAges 18–65
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
CompletedNCT04092686

Investigational Drug for schizophrenia

What is this study about?

Researchers compared SEP-363856 75mg, SEP-363856 100mg and placebo to find out how the approaches affected psychotic symptoms in people with schizophrenia.

This study has finished and is no longer accepting participants.

Multiple locations, including Rogers
SchizophreniaMedication studyAges 18–65
Countries
United States, Bulgaria, Croatia, + 4 others
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
TerminatedNCT04825860

SEP-363856 for schizophrenia

What is this study about?

Researchers are comparing SEP-363856 50 mg, SEP-363856 75 mg and placebo to find out how the approaches affect psychotic symptoms in people with schizophrenia.

This study ended early.

Multiple locations, including Beijing
SchizophreniaMedication studyAges 18–65
Countries
China, Japan, Philippines, + 1 other
Sponsor
Sumitomo Pharma Co., Ltd.
Drug study icon
CompletedNCT04072354

Investigational Drug for schizophrenia

What is this study about?

Researchers compared SEP-363856 50mg, SEP-363856 75mg and placebo to find out how the approaches affected psychotic symptoms in people with schizophrenia.

This study has finished and is no longer accepting participants.

Multiple locations, including Little Rock
SchizophreniaMedication studyAges 13–65
Countries
United States, Bulgaria, Colombia, + 3 others
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. (Pharmaceutical company)
Drug study icon
TerminatedNCT01328093

A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients

Official study title

A Phase 3, Multicenter, Double-Blind Comparison of LY2140023 and Aripiprazole in Patients With DSM-IV-TR Schizophrenia Followed by Open-Label Treatment With LY2140023

This study ended early.

Multiple locations, including Cerritos
SchizophreniaMedication studyAges 18–65
Countries
United States, France, Belgium, + 6 others
Sponsor
Denovo Biopharma LLC

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.