Researchers compare two doses of icalcaprant with placebo to find out whether the medicine improves depression symptoms in adults with bipolarity type I or II. Participants take capsules for six weeks while researchers also monitor side effects.
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Relapse Prevention Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease
Recruiting in the United States
SchizophreniaMedication studyAges 55–90
Countries
United States, France, United Kingdom, + 10 others
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease
Recruiting in the United States
SchizophreniaMedication studyAges 55–90
Countries
United States, Canada, United Kingdom, + 11 others
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
A Multicenter, Randomized, Double-blind, Placebo-controlled, Flexible-dose Study to Assess the Efficacy, Safety, and Tolerability of ITI 1284 in Patients With Psychosis Associated With Alzheimer's Disease
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis
This extension study evaluates the long-term safety and tolerability of KarXT for mania or mania with mixed features in people living with bipolarity type I.
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease
Recruiting in the United States
SchizophreniaMedication studyAges 55–90
Countries
United States, France, Belgium, + 21 others
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Psychosis Associated With Alzheimer's Disease
We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.