This study is looking at evaluate the efficacy of psilocybin on the symptom of anhedonia in individuals with treatment-resistant major depressive disorder for people with depression, Anhedonia, or Treatment Resistant Depression. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.
In United States
DepressionDrugA study involving a medication or substance.From 21 Years to 75 Years
This study exists to understand whether psilocybin treatment is both safe enough and useful enough to take further. Researchers are trying to understand how people respond to psilocybin treatment in practice and what may need to be adjusted.
This study is looking at determine the safety, tolerability, and feasibility of psilocybin therapy in people with Bipolarity II. Participants receive a study treatment and complete follow-up visits and assessments.
In United States
Bipolarity, DepressionDrugFrom 18 Years to 70 Years
This study is comparing Psilocybin with placebo for people with depression or Addiction. Participants receive Psilocybin or placebo and complete study visits and assessments.
In United States
Depression, AddictionDrugFrom 21 Years to 65 Years
This study exists to see whether cognitive behavioural therapy, a structured talking treatment, is workable and worth testing more broadly. Researchers are trying to understand whether cognitive behavioural therapy, a structured talking treatment, can improve attention, thinking, or day-to-day functioning.
This study is looking at whether questionnaires and follow-up can help people with Refractory Depression or Treatment Resistant Depression. Participants receive a study treatment and complete follow-up visits and assessments.
This study exists to explore whether questionnaires and follow-up reports could improve care and understanding. Researchers are trying to understand whether questionnaires and follow-up reports can better prevent setbacks and support longer-term stability.
HopeStage gathers information about mental health clinical trials from the public registries we currently index. We are progressively improving registry coverage, but this does not mean that every study in the world is already included.