The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
This study is recruiting. It focuses on depression and currently lists participation information in Canada.
Key information made simple
This study is comparing Repetitive Transcranial Magnetic Stimulation with Control Group for people with depression or Treatment Resistant Depression. Participants receive Repetitive Transcranial Magnetic Stimulation or Control Group and complete study visits and assessments. Some participants may receive Control Group instead of the study treatment, and direct benefit is not guaranteed.
Your next step
The official record suggests in-person participation through a research setting, with sites including Unity Health Toronto. Participation appears to involve assessments along with scans or samples to help researchers understand patterns more clearly. The main fit is usually being able to understand the study and consent, while common reasons not to take part include pregnancy or breastfeeding and safety concerns that need urgent care first. The official record does not list a formal phase, which usually means this is focused more on feasibility, delivery, or support than a standard drug-development stage.
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
- Recruitment status
- Recruiting
- Estimated enrollment
- Not clearly listed
- Sponsor
- Unity Health Toronto
- Sponsor type
- Unknown or unclear
- Study type
- Device
- Intervention type
- Device / app / digital / technology
- Study phase
- Not clearly listed
- Locations
- Canada
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT06163625
- Official source
- Official registry link
Want help reviewing this study?
Key study information
- Official title
- The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
- Condition
- Depression
- Study status
- Recruiting
- Sponsor / lead affiliation
- Unity Health Toronto
- Location / country
- Canada
- Registry
- ClinicalTrials.gov
- External trial ID
- NCT06163625
Why this study may matter
This study may matter because it adds public evidence around depression. HopeStage presents it as a starting point for understanding the study, checking the official source, and preparing questions with a care team.
For you
Taking part may give access to a new approach being evaluated.
It requires regular visits and structured follow-up.
Requires travel, with in-person participation in Canada.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. It includes a comparison with a control group. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a device, app, or technology?
This appears to be a device / app / digital / technology study. The phase is not clearly listed in the public registry. Phase is mostly relevant for medication studies and some device studies. For this study, it may be more useful to look at what is required, the duration, visits, and eligibility criteria.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 65 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to use a device, app, or digital tool for a defined period. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What should I check about data, monitoring, alerts, and daily use?
If the study uses a device, app, or digital tool, check what data is collected, who can access it, how often you need to use it, and what happens if the tool detects a concerning signal. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Unity Health Toronto, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The registry indicates that this study is currently recruiting. This does not mean you are eligible: the study team must confirm the criteria, available locations, and next steps.
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