RecruitingNCT02994433
Nitrous oxide and brain circuits in resistant depression
About this title
Read the official source — NCT02994433Medication studyAges 18–65United States
Understand this study
Who could participate?
Listed age limits: 18 years to 65 years.
What will I do during this study?
Participants have two one-hour inhalation sessions: one with nitrous oxide and one with a placebo (an inactive comparison treatment) gas. The order is assigned at random, and the sessions are at least one month apart. Brain MRI (magnetic resonance imaging) scans are taken before and after the inhalation sessions, with up to six scans in total. The study includes people with treatment-resistant depression and healthy volunteers.
- Listed locations
- St LouisSee all locations and recruitment
- Study phase
- Phase 1Usually an early study focused on safety, tolerability, dosage, and side effects.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: January 27, 2017
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 60
- Sponsor
- Washington University School of Medicine
- Sponsor type
- University
- Study type
- Drug
- Intervention type
- Device, Drug
- Study phase
- Phase 1Usually an early study focused on safety, tolerability, dosage, and side effects.
- Locations
- United States
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT02994433
- Official title
Show the full official title
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
St Louis
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is Washington University School of Medicine, a university.
Does this study involve medication?
Yes. The study involves medication, including Nitrous Oxide and Placebo gas.
Who can participate?
Listed age limits: 18 years to 65 years.
Is this study still recruiting?
The registry lists this study as recruiting.
