This study is completed in the United States. It is testing ENX-102 for anxiety.
AnxietyDrugFrom 18 Years to 65 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Where are visits, can any be remote, and how much time is needed?
Costs and support
What costs, reimbursement or compensation apply?
Before joining
Questions to ask before joining
What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?
Study clarity
Things to check before joining
Study start dateStarted: July 3, 2023
Recruitment status
Completed
Enrollment listed in the registry
252
Sponsor
Engrail Therapeutics INC
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 65 Years
Official registry ID
NCT05749055
Official title
The ENCALM Trial: A Randomized, Double-blind, Placebo-controlled Monotherapy Trial to Evaluate the Efficacy and Safety of ENX-102 in Patients With Generalized Anxiety Disorder
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT05749055. We help you review the study, but cannot decide medical eligibility.
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
United States · 32 sites
IMA Clinical Research Phoenix
Phoenix, Arizona
Site status: Not listed — confirm with the team
Collaborative Neuroscience Research, LLC (CNS)
Garden Grove, California
Site status: Not listed — confirm with the team
Sun Valley Research Center
Imperial, California
Site status: Not listed — confirm with the team
Alliance Research
Long Beach, California
Site status: Not listed — confirm with the team
NRC Research Institute
Los Angeles, California
Site status: Not listed — confirm with the team
Excell Research, Inc.
Oceanside, California
Site status: Not listed — confirm with the team
Anderson Clinical Research
Redlands, California
Site status: Not listed — confirm with the team
California Neuroscience Research, LLC
Sherman Oaks, California
Site status: Not listed — confirm with the team
Pacific Clinical Research Management Group
Upland, California
Site status: Not listed — confirm with the team
Sunwise Clinical Research
Walnut Creek, California
Site status: Not listed — confirm with the team
Mountain View Clinical Research
Denver, Colorado
Site status: Not listed — confirm with the team
Vertex Clinical Research
Clermont, Florida
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, Inc.
Jacksonville, Florida
Site status: Not listed — confirm with the team
Accel Research Sites Network - Lakeland CRU
Lakeland, Florida
Site status: Not listed — confirm with the team
Accel Research Sites Network - Maitland CRU
Maitland, Florida
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, Inc.
Orlando, Florida
Site status: Not listed — confirm with the team
CenExel iResearch, LLC
Savannah, Georgia
Site status: Not listed — confirm with the team
Collective Medical Research
Overland Park, Kansas
Site status: Not listed — confirm with the team
Boston Clinical Trials
Boston, Massachusetts
Site status: Not listed — confirm with the team
Precise Research Centres
Flowood, Mississippi
Site status: Not listed — confirm with the team
IMA Clinical Research
Las Vegas, Nevada
Site status: Not listed — confirm with the team
SPRI Clinical Trials, LLC
Brooklyn, New York
Site status: Not listed — confirm with the team
Neurobehavioral Research
Cedarhurst, New York
Site status: Not listed — confirm with the team
Richmond Behavioral Associates
Staten Island, New York
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, Inc.
Memphis, Tennessee
Site status: Not listed — confirm with the team
Austin Clinical Trials Partners
Austin, Texas
Site status: Not listed — confirm with the team
FutureSearch Trials of Dallas
Dallas, Texas
Site status: Not listed — confirm with the team
Baylor College of Medicine
Houston, Texas
Site status: Not listed — confirm with the team
Aim Trials
Plano, Texas
Site status: Not listed — confirm with the team
Grayline Research Center
Wichita Falls, Texas
Site status: Not listed — confirm with the team
Alpine Research Organization
Clinton, Utah
Site status: Not listed — confirm with the team
Core Clinical Research
Everett, Washington
Site status: Not listed — confirm with the team
In practice
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Important
Not medical advice
Information from public sources.
Are you the study sponsor? Contact us to update this page: hi@hopestage.com
FAQ
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with anxiety. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving ENX-102, Placebo. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.
Who might this study be for?
This study may concern people with anxiety; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Engrail Therapeutics INC, which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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