RecruitingNCT05786066
Perampanel or placebo before ketamine: a study of brain mechanisms related to mood and suicidal thoughts
About this title
Read the official source — NCT05786066Medication studyAges 21–65United StatesDepression
Understand this study
Who could participate?
Listed age limits: 21 years to 65 years.
What will I do during this study?
This study examines ketamine infusion and perampanel or placebo (an inactive comparison treatment) in people with treatment-resistant depression and current suicidal thoughts, including participants with bipolarity who are in a current depressive episode. Participants receive two infusions at least three weeks apart, with mental-health care required during the study. The registry lists a recruiting site at the VA Connecticut Healthcare System in West Haven. Additional screening and eligibility criteria apply.
- Listed locations
- West HavenSee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: April 3, 2023
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 30
- Sponsor
- Yale University
- Sponsor type
- University
- Study type
- Drug
- Intervention type
- Drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 21 Years to 65 Years
- Official registry ID
- NCT05786066
- Official title
Show the full official title
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
West Haven
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is Yale University, a university.
Does this study involve medication?
Yes. The study involves medication, including Perampanel 6 MG, ketamine and Placebo.
Who can participate?
Listed age limits: 21 years to 65 years.
Is this study still recruiting?
The registry lists this study as recruiting.
