RecruitingNCT05790239
MDMA-assisted or d-amphetamine-assisted therapy for veterans with PTSD
About this title
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Read the official source — NCT05790239This study evaluates the safety and effectiveness of d-amphetamine for people with PTSD.
Medication studyAges 18+United States
Understand this study
What is this study about?
This study evaluates the safety and effectiveness of d-amphetamine for people with PTSD.
Who could participate?
Listed age limits: from 18 years.
What will I do during this study?
Participants are randomly assigned to MDMA-assisted therapy or low-dose d-amphetamine-assisted therapy. At experimental sessions, each group receives its assigned medication in an initial dose and a supplemental dose 1.5 to 2 hours later, alongside therapy.
- Listed locations
- Los Angeles and 1 more locationSee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: March 1, 2025
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 40
- Sponsor
- Stephen Robert Marder
- Sponsor type
- Unknown or unclear
- Study type
- Behavioral
- Intervention type
- Behavioural, Drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- Over 18 Years
- Official registry ID
- NCT05790239
- Official title
Show the full official title
A Randomized, Double-Blind, Single-Site Phase II 2-Arm Study to Compare the Safety and Preliminary Efficacy of Manualized MDMA-Assisted Therapy to Low Dose D-Amphetamine Assisted Therapy in Veterans For The Treatment of Moderate to Severe PTSD
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Los Angeles
Interested in joining this study?
Questions about this study
What is this study about?
This study evaluates the safety and effectiveness of d-amphetamine for people with PTSD.
Who is behind this study?
The study sponsor is Stephen Robert Marder.
Does this study involve medication?
Yes. The study involves medication, including 3,4-methylenedioxymethamphetamine and d-amphetamine.
Who can participate?
Listed age limits: from 18 years.
Is this study still recruiting?
The registry lists this study as recruiting.
