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RecruitingNCT06547489

GATE-251 or Placebo for depression

The registry lists this study as recruiting. Study locations are listed in the United States. Confirm recruitment at each site. It is testing GATE-251 or Placebo for depression.

DepressionDrugFrom 18 Years to 64 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether the Efficacy and Safety of Oral GATE-251 or Placebo may be useful for adults experiencing depression.

What would participation involve?

Participants may receive the Efficacy and Safety of Oral GATE-251 or Placebo, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: February 3, 2025
Recruitment status
Recruiting
Enrollment listed in the registry
164
Sponsor
Syndeio Biosciences, Inc
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 64 Years
Official registry ID
NCT06547489
Official title
A Phase 2, Multicenter, Randomized, Double-blind Evaluation of the Efficacy and Safety of Oral GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder in Adults

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 34 sites
  • University of Alabama at Birmingham
    Birmingham, Alabama
    Site status: Recruiting
  • University of Alabama at Birmingham-Huntsville
    Huntsville, Alabama
    Site status: Active Not Recruiting
  • Wr-Pri, Llc
    Encino, California
    Site status: Withdrawn
  • Irvine Clinical Research
    Irvine, California
    Site status: Recruiting
  • CalNeuro Research Group
    Los Angeles, California
    Site status: Recruiting
  • Pacific Clinical Research Management Group LLC
    Upland, California
    Site status: Terminated
  • Sunwise Clinical Research LLC
    Walnut Creek, California
    Site status: Recruiting
  • MCB Clinical Research Centers, Inc.
    Colorado Springs, Colorado
    Site status: Recruiting
  • Mountain View Clinical Research
    Denver, Colorado
    Site status: Recruiting
  • University of Connecticut School of Medicine Psychiatry Department
    Farmington, Connecticut
    Site status: Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Jacksonville, Florida
    Site status: Recruiting
  • D&H Pompano Research Center, LLC
    Margate, Florida
    Site status: Recruiting
  • Premier Clinical Research Institute, Inc.
    Miami, Florida
    Site status: Recruiting
  • Miami Dade Medical Research Institute
    Miami, Florida
    Site status: Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Orlando, Florida
    Site status: Recruiting
  • CenExel iRS (iResearch Savannah)
    Savannah, Georgia
    Site status: Recruiting
  • Revive Research Institute
    Elgin, Illinois
    Site status: Withdrawn
  • KUMC-Wichita
    Wichita, Kansas
    Site status: Withdrawn
  • Quantum Research Associates Corp.
    Louisville, Kentucky
    Site status: Active Not Recruiting
  • Boston Clinical Trials
    Boston, Massachusetts
    Site status: Withdrawn
  • Mayflower Clinical
    Russells Mills, Massachusetts
    Site status: Recruiting
  • Vector Clinical Trials
    Las Vegas, Nevada
    Site status: Active Not Recruiting
  • Neurobehavioral Research, Inc.
    Cedarhurst, New York
    Site status: Recruiting
  • Insight Clinical Trials LLC
    Independence, Ohio
    Site status: Recruiting
  • Sooner Clinical Research, Inc.
    Oklahoma City, Oklahoma
    Site status: Withdrawn
  • Lehigh Center for Clinical Research
    Allentown, Pennsylvania
    Site status: Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Memphis, Tennessee
    Site status: Withdrawn
  • Austin Clinical Trial Partners
    Austin, Texas
    Site status: Recruiting
  • InSite Clinical Research, LLC
    DeSoto, Texas
    Site status: Recruiting
  • Baylor College of Medicine, Psychiatry and Behavioral Sciences
    Houston, Texas
    Site status: Withdrawn
  • Clinical Trials of Texas LLC
    San Antonio, Texas
    Site status: Withdrawn
  • Grayline Research Center
    Wichita Falls, Texas
    Site status: Recruiting
  • Andes Clinical Research
    Orem, Utah
    Site status: Recruiting
  • Northwest Clinical Research Center
    Bellevue, Washington
    Site status: Withdrawn
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Zelquistinel. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 64 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Syndeio Biosciences, Inc, which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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