RecruitingNCT06668571
IV ketamine and brain chemistry in treatment-resistant depression
About this title
Read the official source — NCT06668571Medication studyAges 18–65United States
Understand this study
Who could participate?
Listed age limits: 18 years to 65 years.
What will I do during this study?
You would be randomly assigned to a 40-minute intravenous infusion of ketamine or saline placebo (an inactive comparison treatment) while in an MRI (magnetic resonance imaging) scanner. Both groups may then choose an additional ketamine infusion, 1 to 7 days later.
- Listed locations
- RochesterSee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: February 10, 2025
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 30
- Sponsor
- Mayo Clinic
- Sponsor type
- Hospital / academic medical center
- Study type
- Drug
- Intervention type
- Drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT06668571
- Official title
Show the full official title
Central and Peripheral GABA and Glutamate Modulation With Intravenous Ketamine for Treatment-Resistant Depression (G2K): A Randomized, Double-Blind, Placebo-Controlled Study
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Rochester
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is Mayo Clinic, a hospital or academic medical center.
Does this study involve medication?
Yes. The study involves medication, including ketamine and Normal Saline.
Who can participate?
Listed age limits: 18 years to 65 years.
Is this study still recruiting?
The registry lists this study as recruiting.
