RecruitingNCT06854224
Suvorexant safety and feasibility for depression with suicide risk
About this title
Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical Trial
Read the official source — NCT06854224Medication studyAges 18–70United StatesSuicide prevention
Understand this study
Who could participate?
The study seeks veterans aged 18 to 70 with major depression, a history of a suicide attempt and suicidal thoughts at screening.
What does the protocol involve?
The protocol calls for daily suvorexant for four weeks and assessments at the medical centre.
- Listed locations
- The BronxSee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: September 1, 2025
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 30
- Sponsor
- Marianne Goodman
- Sponsor type
- Unknown or unclear
- Study type
- Drug
- Intervention type
- Drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 18 Years to 70 Years
- Official registry ID
- NCT06854224
- Official title
Show the full official title
Orexin Antagonism to Target Mechanisms of Suicide Risk: A Proof-of-Concept Clinical Trial
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
The Bronx
Site status as listed in the registry
- James J. Peters Veterans Affairs Medical Center, The Bronx · Currently recruiting
Next step · Check the registry for the research team’s contact details.
Updated by the registry
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is Marianne Goodman.
Does this study involve medication?
Yes. The study involves medication, including Suvorexant (dual orexin receptor antagonist).
Who could participate?
The study seeks veterans aged 18 to 70 with major depression, a history of a suicide attempt and suicidal thoughts at screening.
Is this study still recruiting?
The registry lists this study as recruiting.
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