MDMA-Assisted Therapy for Veterans With PTSD and Addiction: A Controlled study

Based on the public registry summary, this study is trying to understand: The study investigators are conducting the first randomized placebo-controlled trial of MDMA-assisted therapy with a comorbid sample of military Veterans with a co-occurring diagnosis of Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD). This novel. The study team can confirm the exact objective and what it means for you.

This appears to be a behavioral / psychotherapy study involving Full Dose MDMA, MDMA-Assisted psychotherapy, Active Placebo Dose MDMA. It mainly compares psychotherapy or behavioral intervention approaches. The listed phase is PHASE2. Ask the study team what that means in practice for safety, monitoring, and criteria.

The public registry appears to mention tobacco, nicotine, alcohol, cannabis, or another addiction-related topic. Ask the study team whether you need to want to stop, reduce, already be abstinent, or simply meet use-related criteria. Eligibility must be confirmed by the study team.

You may take part in sessions or exercises related to habits, thoughts, emotions, or behaviors. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

Behavioral studies can involve habits, emotions, motivation, stress, sleep, or ways of thinking. Ask whether the intervention could affect your mood or stress, and who to contact if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

This study is sponsored by VA Office of Research and Development, which appears to be a government agency. Sponsor website: https://www.research.va.gov. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

The registry indicates that this study is currently recruiting. This does not mean you are eligible: the study team must confirm the criteria, available locations, and next steps. The registry lists an estimated enrollment of 80 participants.