RecruitingNCT07227103
NRX-101 added to robotic magnetic brain stimulation for treatment-resistant depression
About this title
Read the official source — NCT07227103Medication studyAges 18–80United States
Understand this study
Who could participate?
Listed age limits: 18 years to 80 years.
What will I do during this study?
On the treatment day, your group receives one of three combinations: active magnetic brain stimulation with NRX-101, active stimulation with placebo (an inactive comparison treatment), or simulated stimulation with NRX-101. NRX-101 combines D-cycloserine and lurasidone.
- Listed locations
- Sarasota and 2 more locationsSee all locations and recruitment
- Study phase
- Phase 2 / Phase 3This study spans more than one phase, so it may combine goals such as safety, dosing, and early effectiveness.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateEstimated: December 1, 2026
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 240
- Sponsor
- NeuroRx, Inc.
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Device, Drug
- Study phase
- Phase 2 / Phase 3This study spans more than one phase, so it may combine goals such as safety, dosing, and early effectiveness.
- Locations
- United States
- Age range
- From 18 Years to 80 Years
- Official registry ID
- NCT07227103
- Official title
Show the full official title
A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Sarasota · West Palm Beach · Belmont
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is NeuroRx, Inc.
Does this study involve medication?
Yes. The study involves medication, including NRX-101 and Oral Placebo.
Who can participate?
Listed age limits: 18 years to 80 years.
Is this study still recruiting?
The registry lists this study as recruiting.
