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RecruitingNCT07553637

ALTO-207 for treatment-resistant depression

The registry lists this study as recruiting. Study locations are listed in the United States and in the United Kingdom. Confirm recruitment at each site. It is testing ALTO-207 for treatment-resistant depression.

DepressionDrugFrom 18 Years to 75 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether ALTO-207 may be useful for adults experiencing depression.

What would participation involve?

Participants may receive ALTO-207, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United Kingdom and in the United States.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateEstimated: May 2026
Recruitment status
Recruiting
Enrollment listed in the registry
178
Sponsor
Alto Neuroscience
Sponsor type
Unknown or unclear
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States, United Kingdom
Age range
From 18 Years to 75 Years
Official registry ID
NCT07553637
Official title
A Randomized, Double-blind, Placebo-controlled Trial of ALTO-207 in Adults With Treatment-resistant Depression

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United Kingdom · 10 sites
  • Site 7419
    Antrim
    Site status: Not Yet Recruiting
  • Site 7411
    Birmingham
    Site status: Not Yet Recruiting
  • Site 7414
    Bristol
    Site status: Not Yet Recruiting
  • Site 7412
    Cardiff
    Site status: Not Yet Recruiting
  • Site 7418
    Exeter
    Site status: Not Yet Recruiting
  • Site 7415
    London
    Site status: Not Yet Recruiting
  • Site 7413
    Nottingham
    Site status: Not Yet Recruiting
  • Site 7410
    Oxford
    Site status: Not Yet Recruiting
  • Site 7402
    Prescot
    Site status: Not Yet Recruiting
  • Site 7416
    Sheffield
    Site status: Not Yet Recruiting
United States · 38 sites
  • Site 7074
    Birmingham, Alabama
    Site status: Not Yet Recruiting
  • Site 7173
    Dothan, Alabama
    Site status: Not Yet Recruiting
  • Site 7000
    Phoenix, Arizona
    Site status: Recruiting
  • Site 7153
    Chino, California
    Site status: Not Yet Recruiting
  • Site 7156
    Oakland, California
    Site status: Not Yet Recruiting
  • Site 7082
    Oceanside, California
    Site status: Recruiting
  • Site 7159
    Palo Alto, California
    Site status: Not Yet Recruiting
  • Site 7016
    Sacramento, California
    Site status: Not Yet Recruiting
  • Site 7144
    San Diego, California
    Site status: Recruiting
  • Site 7171
    Valley Village, California
    Site status: Not Yet Recruiting
  • Site 7152
    Saint Augustine, Florida
    Site status: Recruiting
  • Site 7148
    Albany, Georgia
    Site status: Recruiting
  • Site 7146
    Atlanta, Georgia
    Site status: Not Yet Recruiting
  • Site 7064
    Peachtree Corners, Georgia
    Site status: Not Yet Recruiting
  • Site 7141
    Savannah, Georgia
    Site status: Recruiting
  • Site 7169
    Indianapolis, Indiana
    Site status: Not Yet Recruiting
  • Site 7151
    Annapolis, Maryland
    Site status: Recruiting
  • Site 7054
    Pikesville, Maryland
    Site status: Not Yet Recruiting
  • Site 7166
    Worcester, Massachusetts
    Site status: Not Yet Recruiting
  • Site 7155
    Ann Arbor, Michigan
    Site status: Not Yet Recruiting
  • Site 7154
    Bloomfield Hills, Michigan
    Site status: Recruiting
  • Site 7170
    Amherst, New York
    Site status: Not Yet Recruiting
  • Site 7055
    Cedarhurst, New York
    Site status: Not Yet Recruiting
  • Site 7162
    Lewiston, New York
    Site status: Not Yet Recruiting
  • Site 7157
    Syracuse, New York
    Site status: Not Yet Recruiting
  • Site 7143
    Charlotte, North Carolina
    Site status: Recruiting
  • Site 7029
    Cincinnati, Ohio
    Site status: Recruiting
  • Site 7158
    Garfield Heights, Ohio
    Site status: Not Yet Recruiting
  • Site 7172
    East Providence, Rhode Island
    Site status: Not Yet Recruiting
  • Site 7176
    Dallas, Texas
    Site status: Not Yet Recruiting
  • Site 7160
    Fort Worth, Texas
    Site status: Not Yet Recruiting
  • Site 7150
    Galveston, Texas
    Site status: Not Yet Recruiting
  • Site 7175
    Houston, Texas
    Site status: Not Yet Recruiting
  • Site 7145
    Houston, Texas
    Site status: Recruiting
  • Site 7161
    Irving, Texas
    Site status: Recruiting
  • Site 7177
    Fairfax, Virginia
    Site status: Not Yet Recruiting
  • Site 7128
    Seattle, Washington
    Site status: Not Yet Recruiting
  • Site 7163
    South Charleston, West Virginia
    Site status: Not Yet Recruiting
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving ALTO-207, Placebo. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 75 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Alto Neuroscience, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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