RecruitingNCT07592689
DT120 compared with placebo for major depression
About this title
Read the official source — NCT07592689Researchers are comparing DT120, placebo and a simulated comparison procedure to find out how the approaches affect depression symptoms in adults with depression.
Medication studyAges 18–74United States
Understand this study
What is this study about?
Researchers are comparing DT120, placebo and a simulated comparison procedure to find out how the approaches affect depression symptoms in adults with depression.
Who could participate?
This study is for people with depression. Listed age limits: 18 years to 74 years. Other eligibility criteria apply.
- Listed locations
- Little Rock and 29 more locationsSee all locations and recruitment
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: May 10, 2026
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 165
- Sponsor
- Definium Therapeutics US, Inc.
- Sponsor type
- Biotech company
- Study type
- Drug
- Intervention type
- Medication / drug, OTHER
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States
- Age range
- From 18 Years to 74 Years
- Official registry ID
- NCT07592689
- Official title
Show the full official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled, 12-Week Study (Part A) With a 40-Week Open-label Extension (Part B) Evaluating the Efficacy and Safety of Oral DT120 Compared to Placebo in the Treatment of Adults With Major Depressive Disorder - Ascend
Recruitment & locations
RecruitingLittle Rock · Orange · San Diego
25 more locations
- San Francisco
- Santa Monica
- Denver
- Jacksonville
- Maitland
- Orlando
- Tampa
- Atlanta
- Decatur
- Savannah
- Chicago
- Boston
- Worcester
- St Louis
- Las Vegas
- New York
- Cleveland
- Philadelphia
- North Charleston
- Austin
- Draper
- Orem
- Bennington
- Seattle
- Vancouver
A listed location does not confirm current availability.
Questions about this study
What is this study about?
Researchers are comparing DT120, placebo and a simulated comparison procedure to find out how the approaches affect depression symptoms in adults with depression.
Who is behind this study?
The study sponsor is Definium Therapeutics US, Inc.
Does this study involve medication?
Yes. The study involves medication, including DT120.
Who can participate?
This study is for people with depression. Listed age limits: 18 years to 74 years. Other eligibility criteria apply.
Is this study still recruiting?
The registry lists this study as recruiting.
