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RecruitingNCT07592689

DT120 Compared to Placebo for depression

The registry lists this study as recruiting. Study locations are listed in the United States. Confirm recruitment at each site. It is testing DT120 Compared to Placebo for depression.

DepressionDrugFrom 18 Years to 74 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether DT120 may be useful for adults experiencing depression.

What would participation involve?

Participants may receive DT120, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: May 10, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
165
Sponsor
Definium Therapeutics US, Inc.
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug, OTHER
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States
Age range
From 18 Years to 74 Years
Official registry ID
NCT07592689
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled, 12-Week Study (Part A) With a 40-Week Open-label Extension (Part B) Evaluating the Efficacy and Safety of Oral DT120 Compared to Placebo in the Treatment of Adults With Major Depressive Disorder - Ascend

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 30 sites
  • Preferred Research Partners, Inc.
    Little Rock, Arkansas
    Site status: Recruiting
  • ATP Clinical Research Orange County
    Orange, California
    Site status: Not Yet Recruiting
  • Kadima Neuropsychiatry Institute
    San Diego, California
    Site status: Recruiting
  • UCSF Department of Neurology
    San Francisco, California
    Site status: Not Yet Recruiting
  • Psychedelic Science Institute
    Santa Monica, California
    Site status: Recruiting
  • Mountain View Clinical Research, Inc
    Denver, Colorado
    Site status: Recruiting
  • Clinical Neuroscience Solutions, LLC (Jacksonville)
    Jacksonville, Florida
    Site status: Not Yet Recruiting
  • K2 Medical Research (Maitland)
    Maitland, Florida
    Site status: Not Yet Recruiting
  • Clinical Neuroscience Solutions, LLC (Orlando)
    Orlando, Florida
    Site status: Not Yet Recruiting
  • Charter Research
    Orlando, Florida
    Site status: Not Yet Recruiting
  • K2 Medical Research (Tampa)
    Tampa, Florida
    Site status: Not Yet Recruiting
  • CenExel - Atlanta Center for Medical Research
    Atlanta, Georgia
    Site status: Recruiting
  • CenExel - iResearch Atlanta
    Decatur, Georgia
    Site status: Recruiting
  • CenExel - iResearch Savannah
    Savannah, Georgia
    Site status: Recruiting
  • Uptown Research Institute
    Chicago, Illinois
    Site status: Recruiting
  • Adams Clinical Boston
    Boston, Massachusetts
    Site status: Recruiting
  • Adams Clinical Watertown
    Boston, Massachusetts
    Site status: Recruiting
  • Vitalix Clinical
    Worcester, Massachusetts
    Site status: Recruiting
  • Arch Clinical Trials, LLC
    St Louis, Missouri
    Site status: Not Yet Recruiting
  • Redbird Research
    Las Vegas, Nevada
    Site status: Recruiting
  • Adams Clinical Harlem
    New York, New York
    Site status: Recruiting
  • Cleveland Clinic
    Cleveland, Ohio
    Site status: Not Yet Recruiting
  • Adams Clinical Philadelphia
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Coastal Carolina Research
    North Charleston, South Carolina
    Site status: Recruiting
  • Austin Clinical Trial Partners
    Austin, Texas
    Site status: Recruiting
  • Cedar Clinical Research
    Draper, Utah
    Site status: Recruiting
  • Inner Space Research
    Orem, Utah
    Site status: Recruiting
  • Memory Clinic Inc.
    Bennington, Vermont
    Site status: Not Yet Recruiting
  • Seattle Neuropsychiatric Treatment Center
    Seattle, Washington
    Site status: Not Yet Recruiting
  • VA Portland Healthcare System
    Vancouver, Washington
    Site status: Not Yet Recruiting

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In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Placebo, DT120. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Definium Therapeutics US, Inc., which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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