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RecruitingNCT07686263

Xanomeline/Trospium Chloride for schizophrenia

The registry lists this study as recruiting. Study locations are listed in the United States, in the United Kingdom, in Argentina, ... Confirm recruitment at each site. It is testing xanomeline/Trospium Chloride for schizophrenia.

SchizophreniaDrugFrom 18 Years to 65 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether KarXT Treatment may be useful for adults experiencing schizophrenia.

What would participation involve?

Participants may receive KarXT Treatment, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Argentina, in Bulgaria, and in Czechia.

Who is it mainly for?

This study appears to be mainly for adults with schizophrenia.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: August 20, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
472
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, United Kingdom, Argentina, ...
Age range
From 18 Years to 65 Years
Official registry ID
NCT07686263
Official title
A Phase 3 Double-blind, Placebo-controlled Randomized Withdrawal Maintenance Trial of KarXT Treatment in Participants With Schizophrenia

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Study ID: NCT07686263. We help you review the study, but cannot decide medical eligibility.

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Argentina · 4 sites
  • Local Institution - 0175
    Río Cuarto, Córdoba Province
    Site status: Withdrawn
  • Local Institution - 0143
    Buenos Aires
    Site status: Not Yet Recruiting
  • Local Institution - 0002
    Córdoba
    Site status: Not Yet Recruiting
  • Local Institution - 0144
    Santiago del Estero
    Site status: Not Yet Recruiting
Bulgaria · 1 site
  • Local Institution - 0191
    Novi Iskar
    Site status: Not Yet Recruiting
Czechia · 2 sites
  • Local Institution - 0162
    Brno
    Site status: Not Yet Recruiting
  • Local Institution - 0014
    Klecany
    Site status: Not Yet Recruiting
Denmark · 4 sites
  • Local Institution - 0159
    Aarhus, Central Jutland
    Site status: Not Yet Recruiting
  • Local Institution - 0182
    Hovedvejen 19, Frederiksberg
    Site status: Not Yet Recruiting
  • Local Institution - 0157
    Glostrup, Region Sjælland
    Site status: Not Yet Recruiting
  • Local Institution - 0158
    Aalborg
    Site status: Not Yet Recruiting
Poland · 3 sites
  • Local Institution - 0123
    Warsaw, Masovian Voivodeship
    Site status: Not Yet Recruiting
  • Local Institution - 0122
    Bialystok, Podlaskie Voivodeship
    Site status: Not Yet Recruiting
  • Local Institution - 0001
    Poznan
    Site status: Not Yet Recruiting
Romania · 7 sites
  • Local Institution - 0103
    Bucharest, Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0105
    Bucharest, Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0107
    Bucharest, Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0110
    Bucharest, Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0174
    Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0106
    Bucharest
    Site status: Not Yet Recruiting
  • Local Institution - 0109
    Bucharest
    Site status: Not Yet Recruiting
Spain · 3 sites
  • Local Institution - 0112
    Barcelona, Barcelona [Barcelona]
    Site status: Not Yet Recruiting
  • Local Institution - 0167
    Valladolid
    Site status: Not Yet Recruiting
  • Local Institution - 0181
    Zamora
    Site status: Not Yet Recruiting
United Kingdom · 1 site
  • Local Institution - 0094
    Cambridge
    Site status: Not Yet Recruiting
United States · 34 sites
  • Pillar Clinical Research - Bentonville
    Bentonville, Arkansas
    Site status: Recruiting
  • Pillar Clinical Research- Little Rock
    Little Rock, Arkansas
    Site status: Recruiting
  • Local Institution - 0021
    Little Rock, Arkansas
    Site status: Not Yet Recruiting
  • Local Institution - 0153
    Rogers, Arkansas
    Site status: Not Yet Recruiting
  • Local Institution - 0190
    Anaheim, California
    Site status: Not Yet Recruiting
  • Local Institution - 0040
    Bellflower, California
    Site status: Not Yet Recruiting
  • Local Institution - 0188
    Chino, California
    Site status: Not Yet Recruiting
  • Local Institution - 0032
    Culver City, California
    Site status: Not Yet Recruiting
  • Local Institution - 0037
    Garden Grove, California
    Site status: Not Yet Recruiting
  • Local Institution - 0068
    La Habra, California
    Site status: Not Yet Recruiting
  • Local Institution - 0128
    Lemon Grove, California
    Site status: Not Yet Recruiting
  • Local Institution - 0187
    Montclair, California
    Site status: Not Yet Recruiting
  • Local Institution - 0151
    Orange, California
    Site status: Not Yet Recruiting
  • Local Institution - 0030
    Pico Rivera, California
    Site status: Not Yet Recruiting
  • Local Institution - 0185
    Redlands, California
    Site status: Not Yet Recruiting
  • Local Institution - 0186
    Riverside, California
    Site status: Not Yet Recruiting
  • Local Institution - 0193
    Torrance, California
    Site status: Not Yet Recruiting
  • Research Centers of America ( Hollywood )
    Hollywood, Florida
    Site status: Recruiting
  • Local Institution - 0075
    Miami, Florida
    Site status: Withdrawn
  • Local Institution - 0054
    Miami Lakes, Florida
    Site status: Withdrawn
  • Local Institution - 0134
    Miami Springs, Florida
    Site status: Withdrawn
  • Local Institution - 0195
    Oakland Park, Florida
    Site status: Not Yet Recruiting
  • Local Institution - 0044
    West Palm Beach, Florida
    Site status: Not Yet Recruiting
  • Atlanta Center for Medical Research
    Atlanta, Georgia
    Site status: Recruiting
  • Local Institution - 0070
    Sandy Springs, Georgia
    Site status: Not Yet Recruiting
  • Local Institution - 0189
    Savannah, Georgia
    Site status: Not Yet Recruiting
  • Local Institution - 0067
    Chicago, Illinois
    Site status: Not Yet Recruiting
  • Local Institution - 0056
    Chicago, Illinois
    Site status: Not Yet Recruiting
  • Local Institution - 0192
    Gaithersburg, Maryland
    Site status: Not Yet Recruiting
  • Local Institution - 0183
    Cincinnati, Ohio
    Site status: Not Yet Recruiting
  • Local Institution - 0047
    Oklahoma City, Oklahoma
    Site status: Not Yet Recruiting
  • Local Institution - 0049
    Austin, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0194
    Dallas, Texas
    Site status: Not Yet Recruiting
  • Pillar Clinical Research - Richardson
    Richardson, Texas
    Site status: Recruiting
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Xanomeline/Trospium Chloride, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with schizophrenia; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Karuna Therapeutics, Inc., a Bristol Myers Squibb company, which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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