Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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1371studies shown
Showing 51-75 of 1,371
RecruitingNCT05786066

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

This study is comparing Perampanel 6 MG with placebo for people with depression, bipolarity, Post Traumatic Stress Disorder, or Suicidal Ideation. Participants receive Perampanel 6 MG or placebo and complete study visits and assessments.

DepressionDrugFrom 21 Years to 65 Years
Countries
United States
Sponsor
Yale University
Condition
Depression
Active Not RecruitingNCT05172271

Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

This study is comparing MagPro TMS Stimulator and coil with Sham TEST for people with depression, bipolarity, or Unipolar Major Depression. Participants receive MagPro TMS Stimulator and coil or Sham TEST and complete study visits and assessments.

DepressionDeviceFrom 25 Years to 64 Years
Countries
United States
Sponsor
National Institute of Mental Health (NIMH)
Condition
Depression
RecruitingNCT06564818

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

This study is looking at examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with depression for people with depression. Participants receive CYB003 or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 85 Years
Countries
United States
Sponsor
Cybin IRL Limited
Condition
Depression
RecruitingNCT05895747

5-HTP and Creatine for Depression R33 Phase

This study is comparing Low Dose 5-hydroxytryptophan with placebo for people with depression. Participants receive Low Dose 5-hydroxytryptophan or placebo and complete study visits and assessments.

DepressionDrugFrom 18 Years to 65 Years
Countries
United States
Sponsor
University of Utah
Condition
Depression
RecruitingNCT06217198

A Computerized Depression Intervention in Veterans

This study is looking at whether Deprexis can help people with Depression. Participants take part in the therapy or support program and complete follow-up questionnaires or assessments.

DepressionBehavioralOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
RecruitingNCT05507138

A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

This study is looking at whether a digital support tool can help people with Executive Dysfunction, Depression, or Stroke. Participants take part in a digital support tool and complete follow-up assessments.

DepressionOtherFrom 50 Years to 79 Years
Countries
United States
Sponsor
Weill Medical College of Cornell University
Condition
Depression
Not Yet RecruitingNCT06689787

A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms

This study is looking at whether a digital support tool can help people with Psychosocial Functioning, Stress Disorders, Post-Traumatic, or major depression. Participants take part in the therapy or support program and complete follow-up questionnaires or assessments.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
Active Not RecruitingNCT04201106

A Neuroimaging Study of Open-label Placebo in Depressed Adolescents

This study is comparing Open Label Placebo with Rationale with placebo for people with Depression. Participants receive Open Label Placebo with Rationale or placebo and complete study visits and assessments.

DepressionBehavioralFrom 13 Years to 18 Years
Countries
United States
Sponsor
University of California, San Francisco
Condition
Depression
RecruitingNCT06188923

A New Intervention to Improve Function in Veterans With Anxiety and Depression

This observational study is following people with Anxiety and Depression to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
Active Not RecruitingNCT06941844

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

This study is comparing Placebo with placebo for people with depression. Participants receive Placebo or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 74 Years
Countries
United States
Sponsor
Definium Therapeutics US, Inc.
Condition
Depression
Not Yet RecruitingNCT03833206

A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients

This study is looking at evaluate the safety and the effective doses of PDC-1421 in cancer patients with depression. Participants receive a study treatment and complete follow-up visits and assessments.

DepressionOtherFrom 21 Years to 85 Years
Countries
United States
Sponsor
BioLite, Inc.
Condition
Depression
Active Not RecruitingNCT05733546

A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

This observational study is following people with depression to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.

DepressionDrugOver 18 Years
Countries
United States
Sponsor
COMPASS Pathways
Condition
Depression
RecruitingNCT03887715

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

This study is looking at whether a digital support tool can help people with Treatment Resistant Depression. Participants take part in a digital support tool and complete follow-up assessments.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
LivaNova
Condition
Depression